• To understand how Cenforce 100 mg works, we must understand how the process of obtaining erection works. A healthy erection depends on the flow of blood to the penile tissue.

    • When the body gets sexually stimulated, nitric oxide is released in the penis which increases the synthesis of cyclic guanosine monophosphate (cGMP). 
    • cGMP boosts the flow of blood to the penile smooth muscles which makes them relax and causes an erection.
    • To control this phenomenon, an enzyme known as Phosphodiesterase Type 5 is released.
    • PDE 5 impairs the cGMP after a while to result in ejaculation and loss of erection. 

    Cenforce 100 mg is a PDE5 inhibitor that stops the action of the PDE5 enzyme. When cGMP’s release is obstructed, the erection lasts for a longer time.

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    It is used for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH).

    Fildena 100 belongs to the class of drugs known as PDE 5 inhibitors. It blocks the action of the enzyme PDE 5 (that inhibits blood flow) and improves blood circulation. When a person is sexually stimulated, a chemical known as nitric oxide (NO) is released into the penis. Nitric Oxide stimulates the production of cGMP by interacting with the haem group of the enzyme soluble guanylate cyclase (sGC). cGMP is responsible for the contraction and dilation of blood vessels. However, due to the attack of the enzyme PDE 5, cGMP is destroyed. Sildenafil Citrate present in Fildena blocks the action of PDE 5 and allows cGMP to be produced properly. This allows the blood flow easily to the penis. As cGMP is produced, more and more blood flows to the penis. This creates pressure and leads to an erection.

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